| Sooo... Kiwano (horned melon) poisonous or not? Toxicities of KiwanoCucurbitacines are present in some accessions of Cucumis metuliferus, making it extremely bitter. These compounds are very toxic to mammals, however as they are the most bitter substances known they are also feeding deterrents and very rarely eaten by mammals. The non-bitter comercial cultivars do not contain cucurbitacines and are not toxic.There are reports that, as in many plants, the sprouting seed produces a toxic substance in its embryo. In addition, seeds are traditionally also ground into a fine flour and taken with water as a vermifuge to expel tapeworms or other parasites.Suggested uses include mixing with ice cream and maybe a touch of sugar. In Africa the edible ones are eaten for the juicy seed mass and the highly toxic ones are harvested for the seeds which are non-toxic and edible.http://www.hort.purdue.edu/newcrop/CropFactSheets/kiwano.htmlhttp://www.clovegarden.com/ingred/ml_kiwanz.htmlhttp://www.pfaf.org/database/plants.php?Cucumis+metuliferus |