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| Buffers in Medicine (b)? b) Carbon dioxide (CO_2) and bicarbonate (HCO_3^-) concentrations in the bloodstream are physiologically controlled to keep blood pH constant at a normal value of 7.4. Physicians use the following modified form of the Henderson-Hasselbalch equation to track changes in blood pH: pH = pKa + log { [HCO_3^-] / (0.03)(P_(CO_2)) } where [HCO_3^-] is given in millimoles/liter and the arterial blood partial pressure of CO_2 is given in mmHg. The pKa of carbonic acid is 6.1. Hyperventilation causes a physiological state in which the concentration of CO_2 in the bloodstream drops. The drop in the partial pressure of CO_2 constricts arteries and reduces blood flow to the brain, causing dizziness or even fainting. If the normal physiological concentration of HCO_3^- is 24 mM, what is the pH of blood if P_(CO_2) drops to 27.0? |
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| Thread | Thread Starter | Forum | Replies | Last Post |
| Buffers in medicine? | lala | Medicine | 1 | 03-21-2008 09:43 PM |
| Chemistry Help!--Buffers? | Erica. :D | Chemistry | 0 | 03-06-2008 08:44 PM |
| Buffers in Medicine? | Leah B | Medicine | 0 | 03-06-2008 12:13 PM |
| Buffers in Medicine (a)? | cRyStaL c | Medicine | 0 | 03-06-2008 11:32 AM |
| Chemistry buffers? | Jay | Chemistry | 0 | 03-04-2008 08:29 PM |